Genes mediate the association between P3 amplitude and externalizing disorders

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The association between p3 amplitude at age 11 and criminal offending at age 23.

Reduced P3 amplitude to targets is an information-processing deficit associated with adult antisocial behavior and may reflect dysfunction of the temporal-parietal junction. This study aims to examine whether this deficit precedes criminal offending. From a birth cohort of 1,795 children, 73 individuals who become criminal offenders at age 23 and 123 noncriminal individuals were assessed on P3 ...

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The use of endophenotypes to classify individuals at risk for or suffering from psychopathology has been criticized for lacking specificity and predictive utility. This issue is apparent in research on externalizing, a heritable predisposition to disinhibitory psychopathology and personality traits. Numerous studies have shown that P3 amplitude reduction (P3AR) reliably reflects externalizing, ...

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ژورنال

عنوان ژورنال: Psychophysiology

سال: 2007

ISSN: 0048-5772,1469-8986

DOI: 10.1111/j.1469-8986.2006.00471.x